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Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4)

Human alcohol dehydrogenase 4 (ADH4) is one of the key enzymes involved in the metabolism of alcohol. ADH4 is highly expressed in the liver, and previous studies have revealed several cis-acting elements in the proximal promoter region. In this study we have identified a distal upstream enhancer, 4E...

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Autors principals: Pochareddy, Sirisha, Edenberg, Howard J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896571/
https://ncbi.nlm.nih.gov/pubmed/20363298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2010.03.013
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