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A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats
Szechuan peppers contain hydroxy-α-sanshool that imparts desirable tingling, cooling, and numbing sensations. Hydroxy-α-sanshool activates a subset of sensory dorsal root ganglion (DRG) neurons by inhibiting two-pore potassium channels. We presently investigated if a tingle-evoking sanshool analog,...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075278/ https://ncbi.nlm.nih.gov/pubmed/21273322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00922.2010 |
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