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Activation of Lumbar Spinal Wide-Dynamic Range Neurons by a Sanshool Derivative

The enigmatic sensation of tingle involves the activation of primary sensory neurons by hydroxy-α-sanshool, a tingly agent in Szechuan peppers, by inhibiting two-pore potassium channels. Central mechanisms mediating tingle sensation are unknown. We investigated whether a stable derivative of sanshoo...

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Bibliografische gegevens
Hoofdauteurs: Sawyer, Carolyn M., Carstens, Mirela Iodi, Simons, Christopher T., Slack, Jay, McCluskey, T. Scott, Furrer, Stefan, Carstens, E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695645/
https://ncbi.nlm.nih.gov/pubmed/19164099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.91311.2008
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