Mek1 Kinase Activity Functions Downstream of RED1 in the Regulation of Meiotic Double Strand Break Repair in Budding Yeast

Three meiosis-specific chromosomal components in budding yeast, Mek1, Red1, and Hop1, are required for recombination, proper segregation of homologs, and the meiotic recombination checkpoint. Mek1 is a protein kinase. Mutations that increase the size of the ATP binding pocket of Mek1 (mek1-as1) sens...

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Bibliographic Details
Main Authors: Wan, Lihong, de los Santos, Teresa, Zhang, Chao, Shokat, Kevan, Hollingsworth, Nancy M.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2004
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307523/
https://ncbi.nlm.nih.gov/pubmed/14595109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0499
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