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Coordination of Double Strand Break Repair and Meiotic Progression in Yeast by a Mek1-Ndt80 Negative Feedback Loop

During meiosis, homologous chromosomes are physically connected by crossovers and sister chromatid cohesion. Interhomolog crossovers are generated by the highly regulated repair of programmed double strand breaks (DSBs). The meiosis-specific kinase Mek1 is critical for this regulation. Mek1 downregu...

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Bibliographische Detailangaben
Veröffentlicht in:Genetics
Hauptverfasser: Prugar, Evelyn, Burnett, Cameron, Chen, Xiangyu, Hollingsworth, Nancy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419491/
https://ncbi.nlm.nih.gov/pubmed/28249986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.199703
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