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Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombination is initiated by programmed double strand breaks...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Chen, Xiangyu, Gaglione, Robert, Leong, Trevor, Bednor, Lauren, de los Santos, Teresa, Luk, Ed, Airola, Michael, Hollingsworth, Nancy M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289461/
https://ncbi.nlm.nih.gov/pubmed/30496175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007832
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