Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombination is initiated by programmed double strand breaks...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Chen, Xiangyu, Gaglione, Robert, Leong, Trevor, Bednor, Lauren, de los Santos, Teresa, Luk, Ed, Airola, Michael, Hollingsworth, Nancy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289461/
https://ncbi.nlm.nih.gov/pubmed/30496175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007832
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