Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombination is initiated by programmed double strand breaks...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chen, Xiangyu, Gaglione, Robert, Leong, Trevor, Bednor, Lauren, de los Santos, Teresa, Luk, Ed, Airola, Michael, Hollingsworth, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289461/
https://ncbi.nlm.nih.gov/pubmed/30496175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007832
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