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Synthesis and biological evaluation of 2-(3′,4′,5′-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents

The biological importance of microtubules in mitosis, as well as in interphase, makes them an interesting target for the development of anticancer agents. Small molecules such as benzo[b]thiophenes are attractive as inhibitors of tubulin polymerization. Thus, a new class of compounds that incorporat...

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Bibliografiska uppgifter
Huvudupphovsmän: Romagnoli, Romeo, Baraldi, Pier Giovanni, Cara, Carlota Lopez, Hamel, Ernest, Basso, Giuseppe, Bortolozzi, Roberta, Viola, Giampietro
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074966/
https://ncbi.nlm.nih.gov/pubmed/20933308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2010.09.038
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