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Synthesis and biological evaluation of 2-(3′,4′,5′-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents

The biological importance of microtubules in mitosis, as well as in interphase, makes them an interesting target for the development of anticancer agents. Small molecules such as benzo[b]thiophenes are attractive as inhibitors of tubulin polymerization. Thus, a new class of compounds that incorporat...

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Bibliografiske detaljer
Main Authors: Romagnoli, Romeo, Baraldi, Pier Giovanni, Cara, Carlota Lopez, Hamel, Ernest, Basso, Giuseppe, Bortolozzi, Roberta, Viola, Giampietro
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074966/
https://ncbi.nlm.nih.gov/pubmed/20933308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2010.09.038
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