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Mutations affecting the biosynthesis of S-adenosylmethionine cause reduction of DNA methylation in Neurospora crassa.

A temperature-sensitive methionine auxotroph of Neurospora crassa was found in a collection of conditional mutants and shown to be deficient in DNA methylation when grown under semipermissive conditions. The defective gene was identified as met-3, which encodes cystathionine-gamma-synthase. We explo...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Roberts, C J, Selker, E U
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8532524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.23.4818
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