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Synthesis of Signals for De Novo DNA Methylation in Neurospora crassa

Most 5-methylcytosine in Neurospora crassa occurs in A:T-rich sequences high in TpA dinucleotides, hallmarks of repeat-induced point mutation. To investigate how such sequences induce methylation, we developed a sensitive in vivo system. Tests of various 25- to 100-bp synthetic DNA sequences reveale...

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Detalhes bibliográficos
Main Authors: Tamaru, Hisashi, Selker, Eric U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150737/
https://ncbi.nlm.nih.gov/pubmed/12640122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2379-2394.2003
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