Mutations affecting the biosynthesis of S-adenosylmethionine cause reduction of DNA methylation in Neurospora crassa.
A temperature-sensitive methionine auxotroph of Neurospora crassa was found in a collection of conditional mutants and shown to be deficient in DNA methylation when grown under semipermissive conditions. The defective gene was identified as met-3, which encodes cystathionine-gamma-synthase. We explo...
محفوظ في:
| الحاوية / القاعدة: | Nucleic Acids Res |
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| المؤلفون الرئيسيون: | , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Oxford University Press
1995
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| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8532524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.23.4818 |
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