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Methylation and Silencing of Protein Tyrosine Phosphatase Receptor Type O in Chronic Lymphocytic Leukemia

PURPOSE: Previous studies in our laboratory have shown the progressive methylation and suppression of the gene encoding protein tyrosine phosphatase, PTPRO, in the livers of rats fed a methyl-deficient diet that induces hepatocarcinogenesis. Subsequently, we observed the methylation of PTPRO in prim...

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Detalhes bibliográficos
Main Authors: Motiwala, Tasneem, Majumder, Sarmila, Kutay, Huban, Smith, David Spencer, Neuberg, Donna S., Lucas, David M., Byrd, John C., Grever, Michael, Jacob, Samson T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074612/
https://ncbi.nlm.nih.gov/pubmed/17545520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-1720
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