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Cleavage properties of an oligonucleotide containing a bridged internucleotide 5'-phosphorothioate RNA linkage.

An oligonucleotide has been synthesized that contains a single bridging 5'-phosphorothioate at an RNA linkage (5'-ApCpGpGpTpCpTprCpsApCpGpApGpC-3'). This new phosphodiester linkage is found to be particularly susceptible to cleavage when compared with the corresponding oxo, deoxy and...

詳細記述

保存先:
書誌詳細
主要な著者: Kuimelis, R G, McLaughlin, L W
フォーマット: Artigo
言語:Inglês
出版事項: 1995
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC307461/
https://ncbi.nlm.nih.gov/pubmed/8532515
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