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Gene amplification in human cells knocked down for RAD54
BACKGROUND: In mammalian cells gene amplification is a common manifestation of genome instability promoted by DNA double-strand breaks (DSBs). The repair of DSBs mainly occurs through two mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR). We previously showed that defec...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074559/ https://ncbi.nlm.nih.gov/pubmed/21418575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-2-5 |
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