Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells’ Sensitivity to Cisplatin and Radiation In Vivo and In Vitro

PURPOSE: We investigated whether vandetanib, an inhibitor of the tyrosine kinase activities of vascular endothelial growth factor receptor-2 (VEGFR-2), epidermal growth factor receptor (EGFR) and Rearranged during transfection (RET), could augment the antitumor activity of radiation with or without...

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Détails bibliographiques
Auteurs principaux: Sano, Daisuke, Matsumoto, Fumihiko, Valdecanas, David R., Zhao, Mei, Molkentine, David P., Takahashi, Yoko, Hanna, Ehab Y., Papadimitrakopoulou, Vali, Heymach, John, Milas, Luka, Myers, Jeffrey N.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074405/
https://ncbi.nlm.nih.gov/pubmed/21350000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2120
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