Epigenetic Regulation of Vascular Smooth Muscle Cell Proliferation and Neointima Formation by Histone Deacetylase Inhibition

OBJECTIVE: Proliferation of smooth muscle cells (SMC) in response to vascular injury is central to neointimal vascular remodeling. There is accumulating evidence that histone acetylation constitutes a major epigenetic modification for the transcriptional control of proliferative gene expression; how...

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Detalhes bibliográficos
Main Authors: Findeisen, Hannes M., Gizard, Florence, Zhao, Yue, Qing, Hua, Heywood, Elizabeth B., Jones, Karrie L., Cohn, Dianne, Bruemmer, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074344/
https://ncbi.nlm.nih.gov/pubmed/21233448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.221952
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