Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages

Interleukin (IL)-12 is a key factor that induces T helper cell type 1-mediated immunity and inflammatory diseases. In some colitis models, such as IL-10 knock-out (KO) mice, IL-12 triggers intestinal inflammation. An abundant amount of IL-12 is produced by intestinal macrophages in response to stimu...

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Autori principali: Naruse, H, Hisamatsu, T, Yamauchi, Y, Chang, J E, Matsuoka, K, Kitazume, M T, Arai, K, Ando, S, Kanai, T, Kamada, N, Hibi, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
Soggetti:
Translational Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074226/
https://ncbi.nlm.nih.gov/pubmed/21352199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04318.x
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