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Unique CD14(+) intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis

Intestinal macrophages play a central role in regulation of immune responses against commensal bacteria. In general, intestinal macrophages lack the expression of innate-immune receptor CD14 and do not produce proinflammatory cytokines against commensal bacteria. In this study, we identified what we...

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Detalhes bibliográficos
Main Authors: Kamada, Nobuhiko, Hisamatsu, Tadakazu, Okamoto, Susumu, Chinen, Hiroshi, Kobayashi, Taku, Sato, Toshiro, Sakuraba, Atsushi, Kitazume, Mina T., Sugita, Akira, Koganei, Kazutaka, Akagawa, Kiyoko S., Hibi, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391067/
https://ncbi.nlm.nih.gov/pubmed/18497880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34610
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