Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pathway

Mismatch uracil DNA glycosylase (Mug) from Escherichia coli is an initiating enzyme in the base-excision repair pathway. As with other DNA glycosylases, the abasic product is potentially more harmful than the initial lesion. Since Mug is known to bind its product tightly, inhibiting enzyme turnover,...

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Bibliografische gegevens
Hoofdauteurs: Grippon, Seden, Zhao, Qiyuan, Robinson, Tom, Marshall, Jacqueline J. T., O’Neill, Rory J., Manning, Hugh, Kennedy, Gordon, Dunsby, Christopher, Neil, Mark, Halford, Stephen E., French, Paul M. W., Baldwin, Geoff S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074160/
https://ncbi.nlm.nih.gov/pubmed/21112870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq913
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