Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pathway

Mismatch uracil DNA glycosylase (Mug) from Escherichia coli is an initiating enzyme in the base-excision repair pathway. As with other DNA glycosylases, the abasic product is potentially more harmful than the initial lesion. Since Mug is known to bind its product tightly, inhibiting enzyme turnover,...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Grippon, Seden, Zhao, Qiyuan, Robinson, Tom, Marshall, Jacqueline J. T., O’Neill, Rory J., Manning, Hugh, Kennedy, Gordon, Dunsby, Christopher, Neil, Mark, Halford, Stephen E., French, Paul M. W., Baldwin, Geoff S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074160/
https://ncbi.nlm.nih.gov/pubmed/21112870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq913
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы