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Sustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats

Obesity and type 2 diabetes (T2D) are two prevalent chronic diseases that have become a major public health concern in industrialized countries. T2D is characterized by hyperglycemia and islet beta cell dysfunction. Glucagon-like peptide 1 (GLP-1) promotes β cell proliferation and neogenesis and has...

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Detalhes bibliográficos
Main Authors: Moralejo, Daniel, Yanay, Ofer, Kernan, Kelly, Bailey, Adam, Lernmark, Ake, Osborne, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074004/
https://ncbi.nlm.nih.gov/pubmed/21216666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiosc.2010.12.008
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