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Prolonged survival and improved glycemia in BB diabetic rats after early sustained exposure to GLP-1
BACKGROUND: Type I diabetes (T1D) in both humans and BioBreeding (BB) rats is an autoimmune disease that results in complete destruction of islets and insulin dependency for life. Glucagon-like peptide 1 (GLP-1) promotes β cell proliferation and neogenesis and has a potent insulinotropic effect. We...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882674/ https://ncbi.nlm.nih.gov/pubmed/20527046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1466 |
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