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Design, construction, and validation of a modular library of sequence diversity standards for PCR

Methods to measure the sequence diversity of PCR-amplified DNA lack standards for use as assay calibrators and controls. Here, we present a general and economical method for developing customizable DNA standards of known sequence diversity. Standards ranging from 1 to 25,000 sequences were generated...

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Detalhes bibliográficos
Main Authors: Baum, Paul D., Young, Jennifer J., Zhang, Qianjun, Kasakow, Zeljka, McCune, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073996/
https://ncbi.nlm.nih.gov/pubmed/21111699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.11.035
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