Paracrine IL-33 Stimulation Enhances Lipopolysaccharide-Mediated Macrophage Activation

BACKGROUND: IL-33, a member of the IL-1 family of cytokines, provokes Th2-type inflammation accompanied by accumulation of eosinophils through IL-33R, which consists of ST2 and IL-1RAcP. We previously demonstrated that macrophages produce IL-33 in response to LPS. Some immune responses were shown to...

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Detalhes bibliográficos
Main Authors: Ohno, Tatsukuni, Oboki, Keisuke, Morita, Hideaki, Kajiwara, Naoki, Arae, Ken, Tanaka, Shizuko, Ikeda, Masako, Iikura, Motoyasu, Akiyama, Taishin, Inoue, Jun-ichiro, Matsumoto, Kenji, Sudo, Katsuko, Azuma, Miyuki, Okumura, Ko, Kamradt, Thomas, Saito, Hirohisa, Nakae, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073971/
https://ncbi.nlm.nih.gov/pubmed/21494550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018404
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