An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

House dust mite-derived proteases contribute to allergic disorders in part by disrupting epithelial barrier function. Interleukin-33 (IL-33), produced by lung cells after exposure to protease allergens, can induce innate-type airway eosinophilia by activating natural helper (NH) cells, a member of g...

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Veröffentlicht in:Immunity
Hauptverfasser: Morita, Hideaki, Arae, Ken, Unno, Hirotoshi, Miyauchi, Kousuke, Toyama, Sumika, Nambu, Aya, Oboki, Keisuke, Ohno, Tatsukuni, Motomura, Kenichiro, Matsuda, Akira, Yamaguchi, Sachiko, Narushima, Seiko, Kajiwara, Naoki, Iikura, Motoyasu, Suto, Hajime, McKenzie, Andrew N.J., Takahashi, Takao, Karasuyama, Hajime, Okumura, Ko, Azuma, Miyuki, Moro, Kazuyo, Akdis, Cezmi A., Galli, Stephen J., Koyasu, Shigeo, Kubo, Masato, Sudo, Katsuko, Saito, Hirohisa, Matsumoto, Kenji, Nakae, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533925/
https://ncbi.nlm.nih.gov/pubmed/26200013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.06.021
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