An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

House dust mite-derived proteases contribute to allergic disorders in part by disrupting epithelial barrier function. Interleukin-33 (IL-33), produced by lung cells after exposure to protease allergens, can induce innate-type airway eosinophilia by activating natural helper (NH) cells, a member of g...

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Publicado no:Immunity
Main Authors: Morita, Hideaki, Arae, Ken, Unno, Hirotoshi, Miyauchi, Kousuke, Toyama, Sumika, Nambu, Aya, Oboki, Keisuke, Ohno, Tatsukuni, Motomura, Kenichiro, Matsuda, Akira, Yamaguchi, Sachiko, Narushima, Seiko, Kajiwara, Naoki, Iikura, Motoyasu, Suto, Hajime, McKenzie, Andrew N.J., Takahashi, Takao, Karasuyama, Hajime, Okumura, Ko, Azuma, Miyuki, Moro, Kazuyo, Akdis, Cezmi A., Galli, Stephen J., Koyasu, Shigeo, Kubo, Masato, Sudo, Katsuko, Saito, Hirohisa, Matsumoto, Kenji, Nakae, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533925/
https://ncbi.nlm.nih.gov/pubmed/26200013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.06.021
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