Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1β production by DCs

Chitin, which is a major component of house dust mites (HDM), fungi, crustaceans, etc., can activate immune cells, suggesting that it contributes to development of allergic disorders such as asthma. Although the pathophysiological sensitization route of asthmatic patients to allergens is considered...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Arae, Ken, Morita, Hideaki, Unno, Hirotoshi, Motomura, Kenichiro, Toyama, Sumika, Okada, Naoko, Ohno, Tatsukuni, Tamari, Masato, Orimo, Keisuke, Mishima, Yuko, Suto, Hajime, Okumura, Ko, Sudo, Katsuko, Miyazawa, Hiroshi, Taguchi, Haruhiko, Saito, Hirohisa, Matsumoto, Kenji, Nakae, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079063/
https://ncbi.nlm.nih.gov/pubmed/30082755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30259-2
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