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Astrocyte-neuron lactate transport is required for long-term memory formation

We report that in the rat hippocampus learning leads to a significant increase in extracellular lactate levels, which derive from glycogen, an energy reserve selectively localized in astrocytes. Astrocytic glycogen breakdown and lactate release are essential for long-term but not short-term memory f...

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Sonraí Bibleagrafaíochta
Main Authors: Suzuki, Akinobu, Stern, Sarah A., Bozdagi, Ozlem, Huntley, George W., Walker, Ruth H., Magistretti, Pierre J., Alberini, Cristina M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073831/
https://ncbi.nlm.nih.gov/pubmed/21376239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.018
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