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Astrocyte-neuron lactate transport is required for long-term memory formation
We report that in the rat hippocampus learning leads to a significant increase in extracellular lactate levels, which derive from glycogen, an energy reserve selectively localized in astrocytes. Astrocytic glycogen breakdown and lactate release are essential for long-term but not short-term memory f...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073831/ https://ncbi.nlm.nih.gov/pubmed/21376239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.018 |
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