5-Fluorouracil Adjuvant Chemotherapy Does Not Increase Survival in Patients with CpG Island Methylator Phenotype Colorectal Cancer

BACKGROUND & AIMS: 5-FU-based adjuvant chemotherapy does not increase survival times of patients with colorectal tumors with microsatellite instability. We determined the response of patients with colorectal tumors with the CpG island methylator phenotype (CIMP) to 5-FU-based therapy. METHODS: W...

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主要な著者: Jover, Rodrigo, Nguyen, Thuy-Phuong, Pérez-Carbonell, Lucía, Zapater, Pedro, Payá, Artemio, Alenda, Cristina, Rojas, Estefanía, Cubiella, Joaquín, Balaguer, Francesc, Morillas, Juan D., Clofent, Juan, Bujanda, Luis, Reñé, Josep M, Bessa, Xavier, Xicola, Rosa M., Nicolás-Pérez, David, Castells, Antoni, Andreu, Montserrat, Llor, Xavier, Boland, C. Richard, Goel, Ajay
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073650/
https://ncbi.nlm.nih.gov/pubmed/21185836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.12.035
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