5-Fluorouracil Adjuvant Chemotherapy Does Not Increase Survival in Patients with CpG Island Methylator Phenotype Colorectal Cancer

BACKGROUND & AIMS: 5-FU-based adjuvant chemotherapy does not increase survival times of patients with colorectal tumors with microsatellite instability. We determined the response of patients with colorectal tumors with the CpG island methylator phenotype (CIMP) to 5-FU-based therapy. METHODS: W...

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Autors principals: Jover, Rodrigo, Nguyen, Thuy-Phuong, Pérez-Carbonell, Lucía, Zapater, Pedro, Payá, Artemio, Alenda, Cristina, Rojas, Estefanía, Cubiella, Joaquín, Balaguer, Francesc, Morillas, Juan D., Clofent, Juan, Bujanda, Luis, Reñé, Josep M, Bessa, Xavier, Xicola, Rosa M., Nicolás-Pérez, David, Castells, Antoni, Andreu, Montserrat, Llor, Xavier, Boland, C. Richard, Goel, Ajay
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073650/
https://ncbi.nlm.nih.gov/pubmed/21185836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.12.035
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