Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis

Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing neurosteroids, the role of neurosteroids in the clinic...

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Bibliografiset tiedot
Päätekijät: Tokuda, Kazuhiro, O'Dell, Kazuko A., Izumi, Yukitoshi, Zorumski, Charles F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2010
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073626/
https://ncbi.nlm.nih.gov/pubmed/21159950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4101-10.2010
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