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Modulation of BK Channel Gating by the β2 Subunit Involves Both Membrane-Spanning and Cytoplasmic Domains of Slo1

Large-conductance, Ca(2+)- and voltage-sensitive K(+) (BK) channels regulate neuronal functions such as spike frequency adaptation and transmitter release. BK channels are composed of four Slo1 subunits, which contain the voltage-sensing and pore-gate domains in the membrane and Ca(2+) binding sites...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Urvi S., Shi, Jingyi, Cui, Jianmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073600/
https://ncbi.nlm.nih.gov/pubmed/21123563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2323-10.2010
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