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β subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia
Large conductance Ca(2+)-activated K(+) (BK) channels modulate many physiological processes including neuronal excitability, synaptic transmission and regulation of myogenic tone. A gain-of-function (E/D) mutation in the pore-forming α subunit (Slo1) of the BK channel was recently identified and is...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678220/ https://ncbi.nlm.nih.gov/pubmed/19204046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.169243 |
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