Stability and functional effectiveness of phosphorothioate modified duplex DNA and synthetic 'mini-genes'.

Several gene transfer techniques that employ 'naked DNA' molecules have recently been developed and numerous gene therapy protocols that make use of 'naked-DNA' have been proposed. We studied the possibility of enhancing the stability of 'naked DNA vectors' and thus als...

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Autors principals: Ciafrè, S A, Rinaldi, M, Gasparini, P, Seripa, D, Bisceglia, L, Zelante, L, Farace, M G, Fazio, V M
Format: Artigo
Idioma:Inglês
Publicat: 1995
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC307355/
https://ncbi.nlm.nih.gov/pubmed/7479077
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