Stability and functional effectiveness of phosphorothioate modified duplex DNA and synthetic 'mini-genes'.
Several gene transfer techniques that employ 'naked DNA' molecules have recently been developed and numerous gene therapy protocols that make use of 'naked-DNA' have been proposed. We studied the possibility of enhancing the stability of 'naked DNA vectors' and thus also gene transfer and expression...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1995
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307355/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.20.4134 |
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