Stability and functional effectiveness of phosphorothioate modified duplex DNA and synthetic 'mini-genes'.

Several gene transfer techniques that employ 'naked DNA' molecules have recently been developed and numerous gene therapy protocols that make use of 'naked-DNA' have been proposed. We studied the possibility of enhancing the stability of 'naked DNA vectors' and thus also gene transfer and expression...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Ciafrè, S A, Rinaldi, M, Gasparini, P, Seripa, D, Bisceglia, L, Zelante, L, Farace, M G, Fazio, V M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1995
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307355/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.20.4134
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