Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers

In the context of pancreatic cancer, metastasis remains the most critical determinant of resectability, and hence survival. The objective of this study was to determine whether Hedgehog (Hh) signaling plays a role in pancreatic cancer invasion and metastasis because this is likely to have profound c...

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Autori principali: Feldmann, Georg, Dhara, Surajit, Fendrich, Volker, Bedja, Djahida, Beaty, Robert, Mullendore, Michael, Karikari, Collins, Alvarez, Hector, Iacobuzio-Donahue, Christine, Jimeno, Antonio, Gabrielson, Kathleen L., Matsui, William, Maitra, Anirban
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073370/
https://ncbi.nlm.nih.gov/pubmed/17332349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3281
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