Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers

In the context of pancreatic cancer, metastasis remains the most critical determinant of resectability, and hence survival. The objective of this study was to determine whether Hedgehog (Hh) signaling plays a role in pancreatic cancer invasion and metastasis because this is likely to have profound c...

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Autors principals: Feldmann, Georg, Dhara, Surajit, Fendrich, Volker, Bedja, Djahida, Beaty, Robert, Mullendore, Michael, Karikari, Collins, Alvarez, Hector, Iacobuzio-Donahue, Christine, Jimeno, Antonio, Gabrielson, Kathleen L., Matsui, William, Maitra, Anirban
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073370/
https://ncbi.nlm.nih.gov/pubmed/17332349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3281
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