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Senescence of activated stellate cells limits liver fibrosis
Cellular senescence acts as a potent mechanism of tumor suppression; however, its functional contribution to non-cancer pathologies has not been examined. Here we show that senescent cells accumulate in murine livers treated to produce fibrosis, a precursor pathology to cirrhosis. The senescent cell...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073300/ https://ncbi.nlm.nih.gov/pubmed/18724938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.049 |
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