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Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum
Fluctuations in the endogenous levels of kynurenic acid (KYNA), a potent α7 nicotinic and NMDA receptor antagonist, affect extracellular dopamine (DA) concentrations in the rat brain. Moreover, reductions in KYNA levels increase the vulnerability of striatal neurons to NMDA receptor-mediated excitot...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073137/ https://ncbi.nlm.nih.gov/pubmed/19138730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.11.055 |
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