CHANGES IN CORTICAL KYNURENIC ACID BI-DIRECTIONALLY MODULATE PREFRONTAL GLUTAMATE LEVELS AS ASSESSED BY MICRODIALYSIS AND RAPID ELECTROCHEMISTRY

Using two in vivo methods, microdialysis and rapid in situ electrochemistry, this study examined the modulation of extracellular glutamate levels by endogenously produced kynurenic acid (KYNA) in the prefrontal cortex (PFC) of awake rats. Measured by microdialysis, intraperitoneal (i.p.) administrat...

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Hauptverfasser: Konradsson-Geuken, Ȧ., Gash, C. R., Wu, H.-Q., Alexander, K. S., Pellicciari, R., Schwarcz, R., Bruno, J.P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918728/
https://ncbi.nlm.nih.gov/pubmed/20600676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.05.052
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