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Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple-turnover
RNA interference (RNAi) is a conserved gene regulatory mechanism employed by most eukaryotes as a key component of their innate immune response against viruses and retrotransposons. During viral infection, the RNase III-type endonuclease Dicer cleaves viral double-stranded RNA into small interfering...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073027/ https://ncbi.nlm.nih.gov/pubmed/21354178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.038 |
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