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The kinases MEKK2 and MEKK3 regulate Transforming Growth Factor-β-mediated helper T cell differentiation

Mitogen-activated protein kinases (MAPKs) are key mediators of the T cell receptor (TCR) signals but their roles in T helper (Th) cell differentiation are unclear. Here we showed that the MAPK kinase kinases MEKK2 (encoded by Map3k2) and MEKK3 (encoded by Map3k3), negatively regulated transforming g...

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Detalhes bibliográficos
Main Authors: Chang, Xing, Liu, Fang, Wang, Xiaofang, Lin, Aiping, Zhao, Hongyu, Su, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073014/
https://ncbi.nlm.nih.gov/pubmed/21333552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.01.017
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