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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.
A recombinant adenovirus (Ad) expressing Cre recombinase derived from bacteriophage P1 was constructed. To assay the Cre activity in mammalian cells, another recombinant Ad bearing an on/off-switching reporter unit, where a LacZ-expression unit can be activated by the Cre-mediated excisional deletio...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1995
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479022/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3816 |
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