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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.
A recombinant adenovirus (Ad) expressing Cre recombinase derived from bacteriophage P1 was constructed. To assay the Cre activity in mammalian cells, another recombinant Ad bearing an on/off-switching reporter unit, where a LacZ-expression unit can be activated by the Cre-mediated excisional deletio...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1995
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307296/ https://ncbi.nlm.nih.gov/pubmed/7479022 |
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