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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.
A recombinant adenovirus (Ad) expressing Cre recombinase derived from bacteriophage P1 was constructed. To assay the Cre activity in mammalian cells, another recombinant Ad bearing an on/off-switching reporter unit, where a LacZ-expression unit can be activated by the Cre-mediated excisional deletio...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1995
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307296/ https://ncbi.nlm.nih.gov/pubmed/7479022 |
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