Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.

A recombinant adenovirus (Ad) expressing Cre recombinase derived from bacteriophage P1 was constructed. To assay the Cre activity in mammalian cells, another recombinant Ad bearing an on/off-switching reporter unit, where a LacZ-expression unit can be activated by the Cre-mediated excisional deletio...

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Hauptverfasser: Kanegae, Y, Lee, G, Sato, Y, Tanaka, M, Nakai, M, Sakaki, T, Sugano, S, Saito, I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307296/
https://ncbi.nlm.nih.gov/pubmed/7479022
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