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Partially Folded Aggregation Intermediates of Human γD-, γC- and γS-Crystallin Are Recognized and Bound by Human αB-crystallin Chaperone

Human γ-crystallins are long-lived unusually stable proteins of the eye lens exhibiting duplicated, double Greek key domains. The lens also contains high concentrations of the small heat shock chaperone α-crystallin, which suppresses aggregation of model substrates in vitro. Mature-onset cataract is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Acosta-Sampson, Ligia, King, Jonathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072757/
https://ncbi.nlm.nih.gov/pubmed/20621668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.05.067
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