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Synthetic Mimics of Antimicrobial Peptides From Triaryl Scaffolds

In this report, we describe the synthesis of a new series of small amphiphilic aromatic compounds, which mimic the essential properties of cationic antimicrobial peptides using Suzuki-Miyaura coupling. The new design allowed the easy tuning of the conformational restriction, controlled by introducti...

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Autores principales: Thaker, Hitesh D., Sgolastra, Federica, Clements, Dylan, Scott, Richard W., Tew, Gregory N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072574/
https://ncbi.nlm.nih.gov/pubmed/21388190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101410t
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