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Identification of Synthetic Host Defense Peptide Mimics That Exert Dual Antimicrobial and Anti-Inflammatory Activities

A group of synthetic antimicrobial oligomers, inspired by naturally occurring antimicrobial peptides, were analyzed for the ability to modulate innate immune responses to Toll-like receptor (TLR) ligands. These synthetic mimics of antimicrobial peptides (SMAMPs) specifically reduced cytokine product...

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Bibliografiske detaljer
Main Authors: Som, Abhigyan, Navasa, Nicolás, Percher, Avital, Scott, Richard W., Tew, Gregory N., Anguita, Juan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491551/
https://ncbi.nlm.nih.gov/pubmed/22956655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00291-12
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