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Naked1 Antagonizes Wnt Signaling by Preventing Nuclear Accumulation of β-Catenin
Cyto-nuclear shuttling of β-catenin is at the epicenter of the canonical Wnt pathway and mutations in genes that result in excessive nuclear accumulation of β-catenin are the driving force behind the initiation of many cancers. Recently, Naked Cuticle homolog 1 (Nkd1) has been identified as a Wnt-in...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072412/ https://ncbi.nlm.nih.gov/pubmed/21490931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018650 |
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