Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples

BACKGROUND: The retinoblastoma product (RB1) is frequently deregulated in various types of tumors by mutation, deletion, or inactivation through association with viral oncoproteins. The functional loss of RB1 is recognized to be one of the hallmarks that differentiate cancer cells from normal cells....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mizuarai, Shinji, Machida, Takumitsu, Kobayashi, Tsutomu, Komatani, Hideya, Itadani, Hiraku, Kotani, Hidehito
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2011
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072353/
https://ncbi.nlm.nih.gov/pubmed/21447152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-31
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