GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice

These studies investigated the role of gangliosides in governing the steady-state concentration and turnover of unesterified cholesterol in normal tissues and in those of mice carrying the NPC1 mutation. In animals lacking either GM2/GD2 or GM3 synthase, tissue cholesterol concentrations and synthes...

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Detalles Bibliográficos
Autores principales: Li, Hao, Turley, Stephen D., Liu, Benny, Repa, Joyce J., Dietschy, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072295/
https://ncbi.nlm.nih.gov/pubmed/18450647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800180-JLR200
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