Llwytho...

Loss of TRPC1-mediated Ca(2+) influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells

MC degranulation requires the influx of calcium from the extracellular environment. Orai1/STIM1 is essential to MC SOCE, as shown in rat peritoneal MCs, the rat MC lines (RBL-2H3), or in Orai1 null embryo liver-derived, cultured MCs. However, minimal information exists about the role of other calciu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suzuki, Ryo, Liu, Xibao, Olivera, Ana, Aguiniga, Lizath, Yamashita, Yumi, Blank, Ulrich, Ambudkar, Indu, Rivera, Juan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Leukocyte Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072234/
https://ncbi.nlm.nih.gov/pubmed/20571036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0510253
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